KPNA4 Rabbit Polyclonal Antibody

CAT#: TA308726

Rabbit Polyclonal antibody to KPNA4 (karyopherin alpha 4 (importin alpha 3))

Product Images

KPNA4 antibody [C3], C-term detects KPNA4 protein by Western blot analysis. A. 30 ug Rat2 whole cell lysate/extract. 7.5 % SDS-PAGE. KPNA4 antibody [C3], C-term (TA308726) dilution: 1:1000

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  KPNA4 antibody [C3], C-term detects KPNA4 protein by Western blot analysis. A. 30 ug Neuro2A whole cell lysate/extract. B. 30 ug GL261 whole cell lysate/extract. C. 30 ug C8D30 whole cell lysate/extract. D. 30 ug NIH-3T3 whole cell lysate/extract. E. 30 u

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  Sample (30 ug of whole cell lysate). A: 293T. B: HepG2. C: Molt-4. 7.5% SDS PAGE. TA308726 diluted at 1:1500.

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  Immunohistochemical analysis of paraffin-embedded H1299 xenograft, using KPNA4 (TA308726) antibody at 1:500 dilution.

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using QIP1 (TA308726) antibody at 1:200 dilution.

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Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 459 and 521 of KPNA4 (Uniprot ID#O00629)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 58 kDa
• Gene Name: karyopherin subunit alpha 4
• Database Link:
  NP_002259
  Entrez Gene 3840 Human
  UniProt ID O00629
• Background: The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen. [provided by RefSeq]
• Synonyms: IPOA3; QIP1; SRP3
• Note: Seq homology of immunogen across species: Xenopus laevis (92%), Chicken (92%), Bovine (100%)