FANCC Rabbit Polyclonal Antibody

CAT#: TA308740

Rabbit Polyclonal antibody to FANCC (Fanconi anemia, complementation group C)

Product Images

Sample (30 ug of whole cell lysate). A: NIH-3T3. 7.5% SDS PAGE. FANCC antibody. TA308740 diluted at 1:1000.

• 

  FANCC antibody detects FANCC protein by western blot analysis. Various whole cell extracts (30 ug) were separated by 7.5 % SDS-PAGE, and blotted with FANCC antibody (TA308740) diluted by 1:1000

• 

  Immunohistochemical analysis of paraffin-embedded OVCA xenograft, using FANCC (TA308740) antibody at 1:100 dilution.

• 

  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using FANCC (TA308740) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 305 of FANCC (Uniprot ID#Q00597)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 63 kDa
• Gene Name: Fanconi anemia complementation group C
• Database Link:
  NP_000127
  Entrez Gene 14088 MouseEntrez Gene 2176 Human
  UniProt ID Q00597
• Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C. [provided by RefSeq]
• Synonyms: FA3; FAC; FACC

Reference Data

• Protein Families: Druggable Genome