SOCS5 Rabbit Polyclonal Antibody

CAT#: TA308762

Rabbit Polyclonal antibody to SOCS5 (suppressor of cytokine signaling 5)

Product Images

SOCS5 antibody detects SOCS5 protein by Western blot analysis. A. 50 ug mouse testis lysate/extract. 7.5 % SDS-PAGE. SOCS5 antibody (TA308762) dilution: 1:500

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  Sample (30 ug of whole cell lysate). A: Molt-4. 7.5% SDS PAGE. SOCS5 antibody. TA308762 diluted at 1:1000.

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  SOCS5 antibody detects SOCS5 protein by Western blot analysis. A. 30 ug NT2D1 whole cell lysate/extract. B. 30 ug PC-3 whole cell lysate/extract. 7.5 % SDS-PAGE. SOCS5 antibody (TA308762) dilution: 1:500

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  Immunohistochemical analysis of paraffin-embedded Ca922 xenograft, using SOCS5 (TA308762) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 42 of SOCS5
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 61 kDa
• Gene Name: suppressor of cytokine signaling 5
• Database Link:
  NP_659198
  Entrez Gene 500616 RatEntrez Gene 9655 Human
  UniProt ID O75159
• Background: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. [provided by RefSeq]
• Synonyms: CIS6; Cish5; CISH6; SOCS-5
• Note: Seq homology of immunogen across species: Rat (100%), Pig (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Jak-STAT signaling pathway