SOCS4 Rabbit Polyclonal Antibody

CAT#: TA308763

Rabbit polyclonal antibody to SOCS4 (suppressor of cytokine signaling 4)

Product Images

Sample (30 ug of whole cell lysate). A:HeLa S3. 12% SDS PAGE. TA308763 diluted at 1:200

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using SOCS4 (TA308763) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 376 and 440 of SOCS4 (Uniprot ID#Q8WXH5)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 51 kDa
• Gene Name: suppressor of cytokine signaling 4
• Database Link:
  NP_955453
  Entrez Gene 122809 Human
  UniProt ID Q8WXH5
• Background: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
• Synonyms: SOCS7
• Note: Seq homology of immunogen across species: Pig (100%), Chicken (93%), Rhesus Monkey (100%), Bovine (100%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Insulin signaling pathway, Jak-STAT signaling pathway, Type II diabetes mellitus