Mesothelin (MSLN) Rabbit Polyclonal Antibody

CAT#: TA308767

Rabbit polyclonal antibody to Mesothelin (mesothelin)

Product Images

Sample (30 ug of whole cell lysate). A:293T. 7.5% SDS PAGE. TA308767 diluted at 1:1000

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  Immunohistochemical analysis of paraffin-embedded serous OVCA, using MSLN (TA308767) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 44 and 468 of Mesothelin (Uniprot ID#Q13421)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 69 kDa
• Gene Name: mesothelin
• Database Link:
  NP_037536
  Entrez Gene 10232 Human
  UniProt ID Q13421
• Background: An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named mesothelin. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers. This gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
• Synonyms: MPF; SMRP

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane