Collagen III (COL3A1) Rabbit Polyclonal Antibody

CAT#: TA308777

Rabbit Polyclonal antibody to Collagen III alpha1 (collagen, type III, alpha 1)

Product Images

Sample (30 ug of whole cell lysate). A: Hela. 5% SDS PAGE. TA308777 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded NCIN87 xenograft, using Collagen III alpha1 (TA308777) antibody at 1:500 dilution.

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  Collagen III alpha1 antibody [C2C3-2], C-term detects Collagen III alpha1 protein at secreted on mouse intestine by immunohistochemical analysis. Sample: Paraffin-embedded mouse intestine. Collagen III alpha1 antibody [C2C3-2], C-term (TA308777) dilution:

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  Immunofluorescence analysis of methanol-fixed HeLa, using COL3A1 (TA308777) antibody at 1:50 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1247 and 1389 of Collagen III alpha1
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 139 kDa
• Gene Name: collagen type III alpha 1 chain
• Database Link:
  NP_000081
  Entrez Gene 84032 RatEntrez Gene 1281 Human
  UniProt ID P02461
• Background: This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]
• Synonyms: EDS4A
• Note: Seq homology of immunogen across species: Chicken (86%), Rat (92%), Bovine (93%), Xenopus tropicalis (81%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: ECM-receptor interaction, Focal adhesion