IL1RA (IL1RN) Rabbit Polyclonal Antibody

CAT#: TA308778

Rabbit Polyclonal antibody to IL1ra antagonist (interleukin 1 receptor antagonist)

Product Images

IL1 Receptor antagonist antibody detects IL1RN protein by Western blot analysis. A. 30 ug Raji whole cell lysate/extract. 15 % SDS-PAGE. IL1 Receptor antagonist antibody (TA308778) dilution: 1:1000

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  IL1 Receptor antagonist antibody detects IL1RN protein by Western blot analysis. A. 30 ug Neuro2A whole lysate/extract. B. 30 ug C8D30 whole cell lysate/extract. C. 30 ug NIH-3T3 whole cell lysate/extract. D. 30 ug Raw264.7 whole cell lysate/extract. E. 3

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  IL1 Receptor antagonist antibody detects IL1RN protein by Western blot analysis. A. 30 ug PC-12 whole cell lysate/extract. 15 % SDS-PAGE. IL1 Receptor antagonist antibody (TA308778) dilution: 1:1000

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  Immunohistochemical analysis of paraffin-embedded PC3 xenograft, using IL1 Receptor antagonist (TA308778) antibody at 1:500 dilution.

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  Immunofluorescence analysis of methanol-fixed HeLa, using IL1ra antagonist (TA308778) antibody at 1:200 dilution.

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Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 177 of IL1ra antagonist (Uniprot ID#P18510)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 20 kDa
• Gene Name: interleukin 1 receptor antagonist
• Database Link:
  NP_000568
  Entrez Gene 3557 Human
  UniProt ID P18510
• Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
• Synonyms: DIRA; ICIL-1RA; IL-1ra; IL-1ra3; IL-1RN; IL1F3; IL1RA; IRAP; MVCD4

Reference Data

• Protein Families: Druggable Genome, Secreted Protein