RGS4 Rabbit Polyclonal Antibody

CAT#: TA308780

Rabbit polyclonal antibody to RGS4 (regulator of G-protein signaling 4)

Product Images

RGS4 antibody detects RGS4 protein by Western blot analysis. A. 50 ug rat brain lysate/extract. 12 % SDS-PAGE. RGS4 antibody (TA308780) dilution: 1:1000

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  Sample (30 ug of whole cell lysate). A: Raji. 12% SDS PAGE. TA308780 diluted at 1:1000.

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  RGS4 antibody detects RGS4 protein by Western blot analysis. A. 50 ug mouse cerebellum lysate/extract. 12 % SDS-PAGE. RGS4 antibody (TA308780) dilution: 1:1000

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  Immunohistochemical analysis of paraffin-embedded Breast ca, using RGS4 (TA308780) antibody at 1:500 dilution.

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  Immunohistochemical analysis of paraffin-embedded Muscle, using RGS4 (TA308780) antibody at 1:500 dilution.

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 205 of RGS4 (Uniprot ID#P49798)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 23 kDa
• Gene Name: regulator of G-protein signaling 4
• Database Link:
  NP_001106852
  Entrez Gene 5999 Human
  UniProt ID P49798
• Background: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]
• Synonyms: RGP4; SCZD9

Reference Data

• Protein Families: Druggable Genome