DKK3 Rabbit Polyclonal Antibody

CAT#: TA308781

Rabbit Polyclonal antibody to DKK3 (dickkopf homolog 3 (Xenopus laevis))

Product Images

Sample (50 ug of whole cell lysate). A: Mouse brain. 10% SDS PAGE. TA308781 diluted at 1:1000.

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  Sample (30 ug of whole cell lysate). A: A549. 10% SDS PAGE. TA308781 diluted at 1:1000.

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  Immunofluorescence analysis of methanol-fixed A549, using DKK3 (TA308781) antibody at 1:500 dilution.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 6 and 343 of DKK3 (Uniprot ID#Q9UBP4)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 38 kDa
• Gene Name: dickkopf WNT signaling pathway inhibitor 3
• Database Link:
  NP_001018067
  Entrez Gene 50781 MouseEntrez Gene 27122 Human
  UniProt ID Q9UBP4
• Background: This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]
• Synonyms: REIC; RIG
• Note: Seq homology of immunogen across species: Pig (88%), Bovine (89%)

Reference Data

• Protein Families: Druggable Genome, Secreted Protein