XRCC2 Rabbit Polyclonal Antibody

CAT#: TA308789

Rabbit polyclonal antibody to XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2)

Product Images

Sample. A: 30ug of Raji whole cell lysate. 12% SDS PAGE. TA308789 diluted at 1:1000

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  Sample (30 ug of whole cell lysate). A:NIH-3T3. 12% SDS PAGE. TA308789 diluted at 1:1000.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 123 of XRCC2 (Uniprot ID#O43543)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 32 kDa
• Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 2
• Database Link:
  NP_005422
  Entrez Gene 57434 MouseEntrez Gene 499966 RatEntrez Gene 7516 Human
  UniProt ID O43543
• Background: This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene is involved in the repair of DNA double-strand breaks by homologous recombination and it functionally complements Chinese hamster irs1, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents. [provided by RefSeq]
• Synonyms: FANCU
• Note: Seq homology of immunogen across species: Rat (94%), Bovine (94%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Homologous recombination