Protein S (PROS1) Rabbit Polyclonal Antibody

CAT#: TA308822

Rabbit polyclonal antibody to protein S (alpha) (protein S (alpha))

Product Images

Sample (30 ug of whole cell lysate). A: 293T. 7.5% SDS PAGE. TA308822 diluted at 1:1000.

• 

  Protein S alpha antibody [N2C2], Internal detects PROS1 protein at cytosol on hepatoma by immunohistochemical analysis. Sample: Paraffin-embedded hepatoma. Protein S alpha antibody [N2C2], Internal (TA308822) dilution: 1:200.

• 

  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using protein S (alpha) (TA308822) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 209 and 477 of Protein S (Uniprot ID#P07225)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 75 kDa
• Gene Name: protein S (alpha)
• Database Link:
  NP_000304
  Entrez Gene 5627 Human
  UniProt ID P07225
• Background: This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. [provided by RefSeq]
• Synonyms: PROS; PS21; PS22; PS23; PS24; PS25; PSA; THPH5; THPH6

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Complement and coagulation cascades