RAD1 Rabbit Polyclonal Antibody

CAT#: TA308831

Rabbit polyclonal antibody to RAD1 (RAD1 homolog (S. pombe))

Specifications

Product Data

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 77 and 282 of RAD1 (Uniprot ID#O60671)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Purification: Affinity purified by Protein A.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 32 kDa
• Gene Name: RAD1 checkpoint DNA exonuclease
• Database Link:
  NP_002844
  Entrez Gene 19355 MouseEntrez Gene 5810 Human
  UniProt ID O60671
• Background: This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq]
• Synonyms: HRAD1; REC1
• Note: Seq homology of immunogen across species: Rhesus Monkey (100%)

Reference Data

• Protein Families: Druggable Genome