Actin (ACTA1) Rabbit Polyclonal Antibody

CAT#: TA308838

Rabbit polyclonal antibody to alpha-Actin (actin, alpha 1, skeletal muscle)

Product Images

Sample (30 ug of whole cell lysate). A: Raji. 10% SDS PAGE. TA308838 diluted at 1:1000.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment contain a sequence corresponding to a region within amino acids 146 and 355 of alpha Actin (skeletal muscle) (Uniprot ID#P68133)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 42 kDa
• Gene Name: actin, alpha 1, skeletal muscle
• Database Link:
  NP_001091
  Entrez Gene 11459 MouseEntrez Gene 29437 RatEntrez Gene 58 Human
  UniProt ID P68133
• Background: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq]
• Synonyms: ACTA; ASMA; CFTD; CFTD1; CFTDM; MPFD; NEM1; NEM2; NEM3; SHPM
• Note: Seq homology of immunogen across species: Mouse (100%), Rat (100%), Xenopus laevis (100%), Xenopus Tropicalis (100%), Pig (100%), Chicken (100%)

Reference Data

• Protein Families: Stem cell - Pluripotency