gamma Actin (ACTG1) Rabbit Polyclonal Antibody

CAT#: TA308842

Rabbit Polyclonal antibody to gamma Actin (actin, gamma 1)

Product Images

Sample (30 ug of whole cell lysate). A: NIH-3T3. B: JC. C: BCL-1. 10% SDS PAGE. TA308842 diluted at 1:1000.

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  Sample (30 ug of whole cell lysate). A: A431. 10% SDS PAGE. TA308842 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded Spleen, using gamma Actin (TA308842) antibody (10 ug/ml).

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 375 of gamma Actin
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 42 kDa
• Gene Name: actin gamma 1
• Database Link:
  NP_001605
  Entrez Gene 11465 MouseEntrez Gene 287876 RatEntrez Gene 71 Human
  UniProt ID P63261
• Background: Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in nonmuscle cells. [provided by RefSeq]
• Synonyms: ACT; ACTG; BRWS2; DFNA20; DFNA26; HEL-176
• Note: Seq homology of immunogen across species: Rat (100%), Xenopus laevis (100%), Xenopus Tropicalis (100%), Chicken (100%), Bovine (100%)

Reference Data

• Protein Pathways: Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, Tight junction, Vibrio cholerae infection, Viral myocarditis