AK3L1 (AK4) Rabbit Polyclonal Antibody

CAT#: TA308845

Rabbit Polyclonal antibody to Adenylate kinase 3 (adenylate kinase 3-like 1)

Product Images

Sample (30 ug whole cell lysate). A: 293T. B: A431. C: H1299. D: HeLa S3. E: Hep G2. F: Raji. 12% SDS PAGE. TA308845 diluted at 1:1000

• 

  Immunohistochemical analysis of paraffin-embedded gastric cancer N87 xenograft, using AK3L1 (TA308845) antibody at 1:100 dilution.

• 

  Adenylate kinase 3 antibody [N1C3] detects Adenylate kinase 3 protein at mitochondria by immunofluorescent analysis. Sample: HeLa cells were fixed in 2% paraformaldehyde/culture medium at 37°C for 30min. Green: Adenylate kinase 3 protein stained by Adeny

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment contain a sequence corresponding to a region within amino acids 1 and 209 of Adenylate kinase 3 (Uniprot ID#P27144)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25 kDa
• Gene Name: adenylate kinase 4
• Database Link:
  NP_982289
  Entrez Gene 11639 MouseEntrez Gene 205 Human
  UniProt ID P27144
• Background: This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1. [provided by RefSeq]
• Synonyms: AK3; AK3L1; AK3L2; AK 4
• Note: Seq homology of immunogen across species: Mouse (89%), Bovine (92%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Purine metabolism