Complement C3 (C3) Rabbit Polyclonal Antibody

CAT#: TA308855

Rabbit Polyclonal antibody to Complement C3 (complement component 3)

Product Images

C3 antibody [C3], C-term detects C3 protein by western blot analysis. A. 30 ug 293T whole cell extract. B. 30 ug whole cell extract of human C3-transfected 293T cells. 5 % SDS-PAGE. C3 antibody [C3], C-term (TA308855) dilution: 1:20000

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  Immunohistochemical analysis of paraffin-embedded mouse brain, using C3 (TA308855) antibody at 1:500 dilution.

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using C3 (TA308855) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:5000-1:20000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1448 and 1655 of (Uniprot ID#P01024)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 187 kDa
• Gene Name: complement component 3
• Database Link:
  NP_000055
  Entrez Gene 718 Human
  UniProt ID P01024
• Background: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection. [provided by RefSeq]
• Synonyms: AHUS5; ARMD9; ASP; C3a; C3b; CPAMD1; HEL-S-62p

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Complement and coagulation cascades, Systemic lupus erythematosus