Chloride Channel 5 (CLCN5) Rabbit Polyclonal Antibody

CAT#: TA308868

Rabbit polyclonal antibody to chloride channel 5 (chloride channel 5 (nephrolithiasis 2, X-linked, Dent disease))

Product Images

Sample (30 ug of whole cell lysate). A:A431. 7.5% SDS PAGE. TA308868 diluted at 1:500

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 62 and 393 of CLC-5 (Uniprot ID#P51795)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 83 kDa
• Gene Name: chloride voltage-gated channel 5
• Database Link:
  NP_001121371
  Entrez Gene 12728 MouseEntrez Gene 25749 RatEntrez Gene 1184 Human
  UniProt ID P51795
• Background: This gene encodes a member of the ClC family of chloride ion channels and ion transporters. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: ClC-5; CLC5; CLCK2; DENTS; hCIC-K2; NPHL1; NPHL2; XLRH; XRN
• Note: Seq homology of immunogen across species: Mouse (96%), Rabbit (98%), Rat (97%), Xenopus laevis (86%), Xenopus tropicalis (87%)

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane