Cathepsin D (CTSD) Rabbit Polyclonal Antibody

CAT#: TA308871

Rabbit Polyclonal antibody to Cathepsin D (cathepsin D)

Specifications

Product Data

• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 72 and 292 of Cathepsin D (Uniprot ID#P07339)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 45 kDa
• Gene Name: cathepsin D
• Database Link:
  NP_001900
  Entrez Gene 1509 Human
  UniProt ID P07339
• Background: This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq]
• Synonyms: CLN10; CPSD; HEL-S-130P

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Lysosome