Haptoglobin (HP) Rabbit Polyclonal Antibody

CAT#: TA308899

Rabbit Polyclonal antibody to Haptoglobin (haptoglobin)

Product Images

Haptoglobin antibody detects Haptoglobin protein by Western blot analysis. A. 30 ug HeLa whole cell lysate/extract. B. 30 ug HepG2 whole cell lysate/extract. C. 30 ug A375 whole cell lysate/extract. 10% SDS-PAGE. Haptoglobin antibody (TA308899) dilution:

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA:; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 129 and 375 of (Uniprot ID#P00738)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 38 kDa
• Gene Name: haptoglobin
• Database Link:
  NP_001119574
  Entrez Gene 3240 Human
  UniProt ID P00738
• Background: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: BP; HP2ALPHA2; HPA1S

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein, Transmembrane