Hydroxysteroid (17 beta) Dehydrogenase 4 (HSD17B4) Rabbit Polyclonal Antibody

CAT#: TA308904

Rabbit Polyclonal antibody to HSD17B4 (hydroxysteroid (17-beta) dehydrogenase 4)

Product Images

Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. TA308904 diluted at 1:1000.

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  Sample (30 ug of whole cell lysate). A: Hela. 7.5% SDS PAGE. TA308904 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded OVCA, using HSD17B4 (TA308904) antibody at 1:500 dilution.

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  HSD17B4 antibody detects HSD17B4 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 2% paraformaldehyde/culture medium at 37°C for 30min. Green: HSD17B4 protein stained by HSD17B4 antibody (TA308904) diluted at 1:500. Bl

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 18 and 261 of HSD17B4 (Uniprot ID#P51659)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 80 kDa
• Gene Name: hydroxysteroid (17-beta) dehydrogenase 4
• Database Link:
  NP_000405
  Entrez Gene 15488 MouseEntrez Gene 3295 Human
  UniProt ID P51659
• Background: The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. [provided by RefSeq]
• Synonyms: DBP; MFE-2; MPF-2; PRLTS1; SDR8C1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Primary bile acid biosynthesis