MAD2 (MAD2L1) Rabbit Polyclonal Antibody

CAT#: TA308923

Rabbit Polyclonal antibody to Mad2L1 (MAD2 mitotic arrest deficient-like 1 (yeast))

Product Images

Sample (30ug whole cell lysate). A:Hep G2. B:MOLT4. C:Raji. 12% SDS PAGE. TA308923 diluted at 1:1000

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  Immunohistochemical analysis of paraffin-embedded DLD-1 xenograft, using Mad2L1 (TA308923) antibody at 1:500 dilution.

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  MAD2L1 antibody [C2C3], C-term detects MAD2L1 protein at nucleus on rat fore brain by immunohistochemical analysis. Sample: Paraffin-embedded rat fore brain. MAD2L1 antibody [C2C3], C-term (TA308923) dilution: 1:500.

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  Immunofluorescence analysis of human osteosarcoma cell line U2OS, using MAD2L1 (TA308923) antibody at 1:1000 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 142 and 205 of MAD2L1 (Uniprot ID#Q13257)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 24 kDa
• Gene Name: MAD2 mitotic arrest deficient-like 1 (yeast)
• Database Link:
  NP_002349
  Entrez Gene 56150 MouseEntrez Gene 4085 Human
  UniProt ID Q13257
• Background: MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq]
• Synonyms: HSMAD2; MAD2
• Note: Seq homology of immunogen across species: Mouse (92%), Rhesus Monkey (100%), Bovine (100%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation