BNP (NPPB) Rabbit Polyclonal Antibody

CAT#: TA308929

Rabbit polyclonal antibody to BNP (natriuretic peptide precursor B)


USD 415.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IF, WB
Recommended Dilution ICC/IF:1:100-1:1000; WB:1:500-1:3000
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 1 and 134 of BNP (Uniprot ID#P16860)
Formulation 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 15 kDa
Gene Name natriuretic peptide B
Background This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq]
Synonyms BNP
Reference Data
Protein Families Druggable Genome, Secreted Protein, Stem cell - Pluripotency

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