Progesterone Receptor (PGR) Rabbit Polyclonal Antibody

CAT#: TA308936

Rabbit polyclonal antibody to Progesterone receptor (progesterone receptor)

Product Images

Sample (30 ug of whole cell lysate). A: H1299. 7.5% SDS PAGE. TA308936 diluted at 1:500.

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  Immunohistochemical analysis of paraffin-embedded A549 xenograft, using Progesterone receptor (TA308936) antibody at 1:100 dilution.

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  Immunofluorescence analysis of paraformaldehyde-fixed A549, using Progesterone receptor (TA308936) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 18 and 112 of Progesterone Receptor (Uniprot ID#P06401)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 99 kDa
• Gene Name: progesterone receptor
• Database Link:
  NP_000917
  Entrez Gene 18667 MouseEntrez Gene 25154 RatEntrez Gene 5241 Human
  UniProt ID P06401
• Background: This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined. [provided by RefSeq]
• Synonyms: NR3C3; PR
• Note: Seq homology of immunogen across species: Mouse (83%), Rat (92%), Pig (92%), Chimpanzee (93%)

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Protein Pathways: Oocyte meiosis, Progesterone-mediated oocyte maturation