RSK1 p90 (RPS6KA1) Rabbit Polyclonal Antibody

CAT#: TA308953

Rabbit polyclonal antibody to RSK1 p90 (ribosomal protein S6 kinase, 90kDa, polypeptide 1)

Product Images

p90 RSK1 antibody detects p90 RSK1 protein by Western blot analysis. A. 30 ug HepG2 whole cell lysate/extract. 7.5 % SDS-PAGE. p90 RSK1 antibody (TA308953) dilution: 1:1000

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  p90 RSK1 antibody detects p90 RSK1 protein at Cytoplasm and Nucleus by immunofluorescent analysis. Sample: HepG2 cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: p90 RSK1 protein stained by RSK1 antibody (TA308953) diluted at 1:500. Blue:

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 303 and 527 of RSK1
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 84 kDa
• Gene Name: ribosomal protein S6 kinase A1
• Database Link:
  NP_001006666
  Entrez Gene 20111 MouseEntrez Gene 81771 RatEntrez Gene 6195 Human
  UniProt ID Q15418
• Background: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
• Synonyms: HU-1; MAPKAPK1A; p90Rsk; RSK; RSK1
• Note: Seq homology of immunogen across species: Mouse (97%), Chicken (91%), Rat (95%), Bovine (98%)

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Long-term potentiation, MAPK signaling pathway, mTOR signaling pathway, Neurotrophin signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation