Thyroid Hormone Receptor alpha (THRA) Rabbit Polyclonal Antibody

CAT#: TA308957

Rabbit polyclonal antibody to TR Alpha (thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian))

Product Images

Sample (30 ug of whole cell lysate). A: JurKat. 10% SDS PAGE. TA308957 diluted at 1:1000.

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Thyroid Hormone Receptor alpha 2 (TA308957) antibody at 1:500 dilution.

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  Thyroid Hormone Receptor alpha?antibody immunoprecipitates Thyroid Hormone Receptor alpha?protein in IP experiments. IP Sample: HeLa whole cell lysate/extract A. Control with 2 ug of preimmune rabbit IgG B. Immunoprecipitation of Thyroid Hormone Receptor

Specifications

Product Data

• Applications: IF, IP, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 317 and 490 of Thyroid Hormone Receptor alpha 2 (Uniprot ID#P10827)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 55 kDa
• Gene Name: thyroid hormone receptor, alpha
• Database Link:
  NP_003241
  Entrez Gene 7067 Human
• Background: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
• Synonyms: AR7; c-ERBA-1; CHNG6; EAR7; ERB-T-1; ERBA; ERBA1; NR1A1; THRA1; THRA2

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Protein Pathways: Neuroactive ligand-receptor interaction