COBRA1 (NELFB) Mouse Monoclonal Antibody [Clone ID: F7E4]

CAT#: TA309095

Mouse Anti-COBRA1 (NELF-B) Antibody

Product Images

Western blot of neonatal rat brain lysate showing specific immunolabeling

Specifications

Product Data

• Clone Name: F7E4
• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant full length human COBRA1 purified from E. coli
• Formulation: 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
• Purification: Protein G purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 62 kDa
• Gene Name: negative elongation factor complex member B
• Database Link:
  NP_056271
  Entrez Gene 58202 MouseEntrez Gene 311796 RatEntrez Gene 25920 Human
  UniProt ID Q8WX92
• Background: NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]). [supplied by OMIM]
• Synonyms: COBRA1; NELF-B

Reference Data

• Protein Families: Transcription Factors