DOPA Decarboxylase (DDC) Rabbit Polyclonal Antibody

CAT#: TA309108

Rabbit Anti-DOPA Decarboxylase, Human Antibody

Product Images

Western blot of 5 μg of bovine adrenal medulla lysate showing specific immunolabeling of the ~55k DOPA decarboxylase protein.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Bovine, Dog, Guinea Porcine, Human, Rabbit, Rat, Sheep
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
• Formulation: 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 55 kDa
• Gene Name: dopa decarboxylase
• Database Link:
  NP_001076440
  Entrez Gene 24311 RatEntrez Gene 606852 DogEntrez Gene 1644 Human
  UniProt ID P20711
• Background: The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq]
• Synonyms: AADC

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Histidine metabolism, Metabolic pathways, Phenylalanine metabolism, Tryptophan metabolism, Tyrosine metabolism