PGP9.5 (UCHL1) Chicken Polyclonal Antibody

CAT#: TA309272

Chicken Anti-Ubiquitin C-terminal Hydrolase 1 (UCHL1) ck Antibody

Product Images

Western blot of rat hippocampal homogenate showing specific immunolabeling of the ~ 24k UCHL1 protein.

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  Rat mixed neuron/glial cultures stained with anti-UCHL1 antibody (green) and rabbit anti-GFAP antibody (cat. #620-GFAP) (red). Blue is a DNA stain.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1:2,500, IF: 1:500
• Reactivities: Human, Rat
• Host: Chicken
• Isotype: IgY
• Clonality: Polyclonal
• Immunogen: Recombinant full length human UCHL1 purified from E. coli
• Formulation: total IgY fraction in PBS + 10 mM NaN3.
• Purification: Total IgY fraction
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 24 kDa
• Gene Name: ubiquitin C-terminal hydrolase L1
• Database Link:
  NP_004172
  Entrez Gene 29545 RatEntrez Gene 7345 Human
  UniProt ID P09936
• Background: The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.
• Synonyms: HEL-117; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; Uch-L1

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Parkinson's disease