GRP78 (HSPA5) Rabbit Polyclonal Antibody

CAT#: TA309344

Rabbit Polyclonal anti-HSPA5 Antibody

Product Images

Western blot analysis of GRP78 in (from L-R): Recombinant protein, human, dog and mouse tissues using a 1:1000 dilution of TA309344.

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  Western blot analysis of GRP78 in rat tissues, using a 1:1000 dilution of TA309344.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB
• Reactivities: Hamster, Human, Monkey, Mouse, Rabbit, Rat, Xenopus, Fungus, Cow
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Rat GRP78 (Bip) sythetic peptide (amino acids 645-654, C-terminus) conjugated to KLH. Identical to mouse and hamster GRP78 sequenes over residues EEDTSEKDEL.
• Formulation: PBS pH7.4, 50% glycerol
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: heat shock protein family A (Hsp70) member 5
• Database Link:
  NP_005338
  Entrez Gene 14828 MouseEntrez Gene 25617 RatEntrez Gene 703193 MonkeyEntrez Gene 3309 Human
  UniProt ID P11021
• Background: The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.
• Synonyms: BIP; GRP78; HEL-S-89n; MIF2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Antigen processing and presentation, Prion diseases