HSP90AB1 Mouse Monoclonal Antibody [Clone ID: 8D3]

CAT#: TA309394

Mouse Monoclonal anti-HSP90AB1 Antibody

Product Images

Hsp90 complex isolation (IP) from rabbit reticulocyte lysate (8D3), SDS Page.

Specifications

Product Data

• Clone Name: 8D3
• Applications: IP
• Recommended Dilution: IP
• Reactivities: Human, Mouse, Rabbit, Rat
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: Ah receptor (Aryl hydrocarbon receptor)
• Formulation: PBS pH7.2, 50% glycerol
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: heat shock protein 90kDa alpha family class B member 1
• Database Link:
  NP_031381
  Entrez Gene 15516 MouseEntrez Gene 301252 RatEntrez Gene 3326 Human
  UniProt ID P08238
• Background: HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1 (MIM 140571), an inducible form, and HSP90AB1, a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219) (Chen et al., 2005 [PubMed 16269234]). [supplied by OMIM]
• Synonyms: D6S182; HSP84; HSP90B; HSPC2; HSPCB

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Antigen processing and presentation, NOD-like receptor signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer