IRS1 Rabbit Polyclonal Antibody

CAT#: TA309986

Rabbit anti-IRS1 (Phospho-Ser312) polyclonal antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from 293 cells, using IRS-1 (phospho-Ser312) antibody (Lanes 1 and 2).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:1000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 312 (A-T-SP-P-A).
• Formulation: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: insulin receptor substrate 1
• Database Link:
  NP_005535
  Entrez Gene 16367 MouseEntrez Gene 25467 RatEntrez Gene 3667 Human
  UniProt ID P35568
• Synonyms: HIRS-1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Adipocytokine signaling pathway, Insulin signaling pathway, Neurotrophin signaling pathway, Type II diabetes mellitus