MEK6 (MAP2K6) Rabbit Polyclonal Antibody

CAT#: TA309987

Rabbit anti-MAP2K6 (MKK6, Phospho-Ser207) polyclonal antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from MDA-MB-435 cells untreated or treated with UV, using MKK antibody (Lanes 1 and 2) and MKK (phospho-Ser207) antibody (Lanes 3 and 4).

• 

  Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using MKK6 (phospho-Ser207) antibody.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500~1:1000, IHC: 1:50~1:100
• Reactivities: Human, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from humanMKK6 around the phosphorylation site of serine 207 (V-D-SP-V-A).
• Formulation: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: mitogen-activated protein kinase kinase 6
• Database Link:
  NP_002749
  Entrez Gene 114495 RatEntrez Gene 5608 Human
  UniProt ID P52564
• Synonyms: MAPKK6; MEK6; MKK6; PRKMK6; SAPKK-3; SAPKK3

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Amyotrophic lateral sclerosis (ALS), Fc epsilon RI signaling pathway, GnRH signaling pathway, MAPK signaling pathway, Toll-like receptor signaling pathway