DNA PKcs (PRKDC) Rabbit Polyclonal Antibody

CAT#: TA309996

Rabbit anti-PRKDC (DNA PKcs, Phospho-Thr2609) polyclonal antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from K562 cells untreated or treated with hydroxyurea, using DNAPKcs antibody (Lanes 1 and 2) and DNA PKcs (phospho-Thr2609) antibody (Lanes 3 and 4).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:1000
• Reactivities: Human
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from humanDNA PKcs around the phosphorylation site of threonine 2609 (V-E-TP-Q-A).
• Formulation: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatography using non-phosphopeptide corresponding to the phosphorylation site.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: protein kinase, DNA-activated, catalytic polypeptide
• Database Link:
  NP_008835
  Entrez Gene 5591 Human
  UniProt ID P78527
• Synonyms: DNA-PKcs; DNAPK; DNPK1; HYRC; HYRC1; IMD26; p350; XRCC7

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Cell cycle, Non-homologous end-joining