GAPDH Mouse Monoclonal Antibody [Clone ID: 1D4]

CAT#: TA310153

Anti-GAPDH mouse mAb (Loading control)


USD 235.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Clone Name 1D4
Applications WB
Recommended Dilution WB
Reactivities Human, Monkey, Mouse, Rat, Dog
Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Purified pig GAPDH
Formulation PBS, pH 7.4 with 0.05% sodium azide
Concentration lot specific
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name glyceraldehyde-3-phosphate dehydrogenase
Background Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. Recent evidence suggests that it also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export (1). GAPDH has also been implicated in playing a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer’s and Huntington’s disease (2). GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.
Synonyms G3PD; GAPD; HEL-S-162eP
Reference Data
Protein Families ES Cell Differentiation/IPS
Protein Pathways Alzheimer's disease, Glycolysis / Gluconeogenesis, Metabolic pathways

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