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AGL Rabbit Monoclonal Antibody [Clone ID: EPR8880]
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Other products for "AGL"
Specifications
| Product Data | |
| Clone Name | EPR8880 |
| Applications | Assay, IHC, WB |
| Recommended Dilution | WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250; FC: 1:100 - 1:500 |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthetic peptide corresponding to residues in human AGL was used as an immunogen. |
| Formulation | pH: 7.20 Preservative: 0.01% Sodium azide Constituents: 49% PBS, 50% Glycerol, 0.05% BSA |
| Purification | Tissue culture supernatant |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 175 kDa |
| Gene Name | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| Database Link | |
| Background | AGL is the glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in AGL are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing (1). |
| Synonyms | GDE |
| Note | Is unsuitable for IP. |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Starch and sucrose metabolism |
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