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CD48 Rabbit Monoclonal Antibody [Clone ID: EPR4108]
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Other products for "CD48"
Specifications
| Product Data | |
| Clone Name | EPR4108 |
| Applications | IHC, WB |
| Recommended Dilution | WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC: 1:250 - 1:500 |
| Reactivities | Human |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthetic peptide corresponding to residues in human CD48 was used as an immunogen. |
| Formulation | pH: 7.40 Preservative: 0.01% Sodium azide Constituents: 50% Glycerol, 0.05% BSA |
| Purification | Tissue culture supernatant |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 28 kDa |
| Gene Name | CD48 molecule |
| Database Link | |
| Background | CD48 (BLAST1) is an activation-associated, glycosyl-phosphatidyl-inositol (GPI)-anchored cell surface glycoprotein expressed primarily in mitogen-stimulated human lymphocytes (1, 2). As a member of the CD2 family, CD48 interacts with CD2 as a low-affinity ligand on the surface of antigen-presenting cells (2, 3). In addition, it is a high-affinity ligand for 2B4. CD48–2B4 interactions can modulate T cell, B cell, and natural killer (NK) cell functions and cross-talk (4). |
| Synonyms | BCM1; BLAST; BLAST1; hCD48; mCD48; MEM-102; SLAMF2 |
| Note | Is unsuitable for Flow Cyt. |
| Reference Data | |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Natural killer cell mediated cytotoxicity |
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