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DHFR Rabbit Monoclonal Antibody [Clone ID: EPR5285]
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Specifications
| Product Data | |
| Clone Name | EPR5285 |
| Applications | IHC, WB |
| Recommended Dilution | WB: 1:10000 - 1:50000; IHC-P: 1:100 - 1:250; ICC: 1:25 - 1:50 |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthetic peptide corresponding to residues in human DHFR was used as an immunogen. |
| Formulation | pH: 7.40 Preservative: 0.01% Sodium azide Constituents: 50% Glycerol, 0.05% BSA |
| Purification | Tissue culture supernatant |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 21 kDa |
| Gene Name | dihydrofolate reductase |
| Database Link | |
| Background | Dihydrofolate reductase (DHFR) converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. DHFR deficiency has been linked to megaloblastic anemia (1). |
| Synonyms | DHFRP1; DYR |
| Note | Is unsuitable for Flow Cyt or IP. |
| Reference Data | |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Protein Pathways | Folate biosynthesis, Metabolic pathways, One carbon pool by folate |
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