FLAP (ALOX5AP) Rabbit Monoclonal Antibody [Clone ID: EPR5640]

CAT#: TA310491

Rabbit Monoclonal antibody against FLAP

Product Images

Western blot - Anti-FLAP antibody [EPR5640]; All lanes : Anti-FLAP antibody [EPR5640] at 1/1000 dilution.Lane 1 : Raji cell lysates.Lane 2 : THP1 cell lysates.Lane 3 : HepG2 cell lysates.Lane 4 : K562 cell lysates.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 18 kDa.

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  Other-Anti-FLAP antibody [EPR5640] (TA310491); Equilibrium disassociation constant (KD).

Specifications

Product Data

• Clone Name: EPR5640
• Applications: Assay, WB
• Recommended Dilution: WB: 1:1000 - 1:10000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide corresponding to residues in human FLAP was used as an immunogen.
• Formulation: PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: arachidonate 5-lipoxygenase activating protein
• Database Link:
  NP_001620
  Entrez Gene 241 Human
  UniProt ID P20292
• Background: FLAP, along with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites that have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. It localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation (1).
• Synonyms: FLAP
• Note: Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.

Reference Data

• Protein Families: Druggable Genome, Transmembrane