POT1 Rabbit Monoclonal Antibody [Clone ID: EPR6319]

CAT#: TA310771

Rabbit Monoclonal antibody against POT1

Product Images

Western blot - Anti-POT1 antibody [EPR6319]; All lanes : Anti-POT1 antibody [EPR6319] at 1/1000 dilution.Lane 1 : K562 cell lysate.Lane 2 : HepG2 cell lysate.Lane 3 : 293T cell lysate.Lane 4 : HeLa cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 71 kDa.

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  Figure from citation: Western blot analysis of POT1 protein expression by using anti-POT1 antibody in NCI-N87 cells. View Citation

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  Other-Anti-POT1 antibody [EPR6319] (TA310771); Equilibrium disassociation constant (KD).

Specifications

Product Data

• Clone Name: EPR6319
• Applications: Assay, WB
• Recommended Dilution: WB: 1:1000 - 1:10000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide corresponding to residues in human POT1 was used as an immunogen.
• Formulation: PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: protection of telomeres 1
• Database Link:
  NP_001036059
  Entrez Gene 25913 Human
  UniProt ID Q9NUX5
• Background: POT1 is a member of the telombin family and is a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression (1).
• Synonyms: CMM10; GLM9; HPOT1
• Note: Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.