Estrogen Receptor 1 (ESR1) Rabbit Polyclonal Antibody

CAT#: TA311733

Rabbit polyclonal Estrogen Receptor-a (Tyr537) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from 293 cells, using Estrogen Receptor-a (Phospho-Tyr537) antibody.The lane on the right is treated with the synthesized peptide.

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  Western blot analysis of extracts from K562 cells (Lane 2), using Estrogen Receptor-a (Phospho-Tyr537) Antibody. The lane on the left is treated with synthesized peptide.

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  Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Estrogen Receptor-a (Phospho-Tyr537) antibody.The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:1000
• Reactivities: Human, Mouse
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human ER-a around the phosphorylation site of tyrosine 537 (P-L-YP-D-L).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: estrogen receptor 1
• Database Link:
  NP_000116
  Entrez Gene 13982 MouseEntrez Gene 2099 Human
  UniProt ID P03372
• Synonyms: ER; Era; ESR; ESRA; ESTRR; NR3A1
• Note: Estrogen Receptor-. (Phospho-Tyr537) antibody detects endogenous levels of ER-. only when phosphorylated at tyrosine 537.

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors