CD18 (ITGB2) Rabbit Polyclonal Antibody

CAT#: TA311741

Rabbit polyclonal CD18/ITGB2 (Thr758) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from COS cells, treated with EGF (200ng/ml, 30mins), using CD18/ITGB2 (Phospho-Thr758) antibody.The lane on the right is treated with the synthesized peptide.

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  Immunofluorescence analysis of HepG2 cells, using CD18/ITGB2 (Phospho-Thr758) antibody.The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1:500~1:3000, IF: 1:100~1:500, ELISA: 1:40000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human CD18/ITGB2 around the phosphorylation site of threonine 758 (S-A-TP-T-T).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: integrin subunit beta 2
• Database Link:
  NP_000202
  Entrez Gene 16414 MouseEntrez Gene 309684 RatEntrez Gene 3689 Human
  UniProt ID P05107
• Synonyms: CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7
• Note: CD18/ITGB2 (Phospho-Thr758) antibody detects endogenous levels of CD18/ITGB2 only when phosphorylated at threonine 578.

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Regulation of actin cytoskeleton, Viral myocarditis