IRF3 Rabbit Polyclonal Antibody

CAT#: TA311896

Rabbit polyclonal IRF-3 (Ser385) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from HT-29 cells, treated with insulin (0.01U/ml, 15mins), using IRF-3 (Phospho-Ser385) antibody.The lane on the right is treated with the synthesized peptide.

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  Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using IRF-3 (Phospho-Ser385) antibody.The picture on the right is treated with the synthesized peptide.

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  Immunofluorescence analysis of HeLa cells, using IRF-3 (Phospho-Ser385) antibody.The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1:500~1:3000, IHC: 1:50~1:100, IF: 1:100~1:500, ELISA: 1:10000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human IRF-3 around the phosphorylation site of serine 385 (G-A-SP-S-L).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interferon regulatory factor 3
• Database Link:
  NP_001562
  Entrez Gene 54131 MouseEntrez Gene 292892 RatEntrez Gene 3661 Human
  UniProt ID Q14653
• Synonyms: interferon regulatory factor 3; MGC94729
• Note: IRF-3 (Phospho-Ser385) antibody detects endogenous levels of IRF-3 only when phosphorylated at serine 385.

Reference Data

• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Cytosolic DNA-sensing pathway, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway