Her2 (ERBB2) Rabbit Polyclonal Antibody

CAT#: TA312249

Rabbit polyclonal HER2 (Tyr877) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from HeLa cells and HepG2 cells, using HER2 (Phospho- Tyr877) Antibody.The lane on the right is treated with the synthesized peptide.

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  Immunohistochemical analysis of paraffin-embedded breast carcinoma, using HER2 (Phospho-Tyr877) Antibody. Left: Untreated; Right: Treated with synthesized phosphopeptide.The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:10000, IP: Various Dilution
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human HER2 around the phosphorylation site of Tyrosine 877 (T-E-YP-H-A).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: erb-b2 receptor tyrosine kinase 2
• Database Link:
  NP_004439
  Entrez Gene 13866 MouseEntrez Gene 24337 RatEntrez Gene 2064 Human
  UniProt ID P04626
• Synonyms: CD340; HER-2; HER2; MLN 19; NEU; neu; NGL; TKR1
• Note: HER2(Phospho-Tyr877) Antibody detects endogenous levels of HER2 only when phosphorylated at Tyrosine 877.

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Adherens junction, Bladder cancer, Calcium signaling pathway, Endometrial cancer, ErbB signaling pathway, Focal adhesion, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer