NOTCH1 Rabbit Polyclonal Antibody

CAT#: TA312382

Rabbit polyclonal Notch 1 (Cleaved-Val1744) antibody

Product Images

Immunohistochemical analysis of paraffin-embedded human brain tissue using Notch 1 (cleaved-Val1744) antibody.The picture on the right is treated with the synthesized peptide.

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  Western blot analysis of extracts from NIH/3T3 cells, treated with etoposide (25µM, 1hour), using Notch 1 (cleaved-Val1744) antibody.The lane on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:5000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized peptide derived from human Notch 1.
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: notch 1
• Database Link:
  NP_060087
  Entrez Gene 18128 MouseEntrez Gene 25496 RatEntrez Gene 4851 Human
  UniProt ID P46531
• Synonyms: AOS5; AOVD1; hN1; TAN1
• Note: Notch 1 (cleaved-Val1744) antibody detects endogenous levels of fragment of activated Notch 1 resulting from cleavage adjacent to Val1744.

Reference Data

• Protein Families: Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway
• Protein Pathways: Dorso-ventral axis formation, Notch signaling pathway, Prion diseases