Caspase 8 (CASP8) Rabbit Polyclonal Antibody

CAT#: TA312452

Rabbit polyclonal Caspase 8 (Tyr380) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from LOVO cells, treated with UV (15mins), using Caspase 8 (Phospho-Tyr380) antibody.The lane on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:3000, ELISA: 1:10000
• Reactivities: Human
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Caspase 8 around the phosphorylation site of tyrosine 380 (Q-P-YP-L-E).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: caspase 8
• Database Link:
  NP_203521
  Entrez Gene 841 Human
  UniProt ID Q14790
• Synonyms: FLICE; MACH; MCH5; MGC78473
• Note: Caspase 8 (Phospho-Tyr380) antibody detects endogenous levels of Caspase 8 only when phosphorylated at tyrosine 380.

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Alzheimer's disease, Apoptosis, Huntington's disease, NOD-like receptor signaling pathway, p53 signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Viral myocarditis