Caspase 1 (CASP1) Rabbit Polyclonal Antibody

CAT#: TA312625

Rabbit polyclonal Caspase 1 (Ser376) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from 293 cells, using Caspase 1 (Phospho-Ser376) antibody.The lane on the right is treated with the synthesized peptide.

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  Immunohistochemistry analysis of paraffin-embedded human brain tissue using Caspase 1 (Phospho-Ser376) antibody.The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:20000
• Reactivities: Human, Mouse
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Caspase 1 around the phosphorylation site of serine 376 (R-F-SP-F-E).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: caspase 1
• Database Link:
  NP_150637
  Entrez Gene 12362 MouseEntrez Gene 834 Human
  UniProt ID P29466
• Synonyms: ICE; IL1BC; P45
• Note: Caspase 1 (Phospho-Ser376) antibody detects endogenous levels of Caspase 1 only when phosphorylated at serine 376

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Amyotrophic lateral sclerosis (ALS), Cytosolic DNA-sensing pathway, NOD-like receptor signaling pathway