GAB2 Rabbit Polyclonal Antibody

CAT#: TA312746

Rabbit polyclonal Gab2 (Ser623) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from HepG2 cells, treated with PMA (125ng/ml, 30mins), using Gab2 (Phospho-Ser623) antibody.The lane on the right is treated with the synthesized peptide.

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  Western blot analysis of extracts from 293 cells (Lane 2), HeLa cells (Lane 3) and HepG2 cells (Lane 4), using Gab2 (Phospho-Ser623) Antibody. The lane on the left is treated with synthesized peptide.

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  Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Gab2 (Phospho-Ser623) antibody.The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:1000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Gab2 around the phosphorylation site of serine 623 (PS-SP-P-S).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: GRB2 associated binding protein 2
• Database Link:
  NP_036428
  Entrez Gene 14389 MouseEntrez Gene 84477 RatEntrez Gene 9846 Human
  UniProt ID Q9UQC2
• Synonyms: KIAA0571
• Note: Gab2 (Phospho-Ser623) antibody detects endogenous levels of Gab2 only when phosphorylated at serine 623.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Chronic myeloid leukemia, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis