IRS1 Rabbit Polyclonal Antibody

CAT#: TA312870

Rabbit polyclonal IRS-1 (Ser307) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from K562 cells, using IRS-1 (Phospho-Ser307) antibody.The lane on the right is treated with the synthesized peptide.

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  Immunofluorescence analysis of COS-7 cells, using IRS-1 (Phospho-Ser307) antibody.The picture on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1:500~1:1000, IF: 1:100~1:500, ELISA: 1:10000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 307 (T-E-SP-I-T).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: insulin receptor substrate 1
• Database Link:
  NP_005535
  Entrez Gene 16367 MouseEntrez Gene 25467 RatEntrez Gene 3667 Human
  UniProt ID P35568
• Synonyms: HIRS-1
• Note: IRS-1 (Phospho-Ser307) antibody detects endogenous levels of IRS-1 only when phosphorylated at serine 307.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Adipocytokine signaling pathway, Insulin signaling pathway, Neurotrophin signaling pathway, Type II diabetes mellitus