ZAP70 Rabbit Polyclonal Antibody

CAT#: TA313217

Rabbit polyclonal Zap-70 (Tyr319) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from Jurkat cells, using Zap-70 (Phospho-Tyr319) antibody.The lane on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:3000, ELISA: 1:1000
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Zap-70 around the phosphorylation site of tyrosine 319 (S-P-YP-S-D).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: zeta chain of T cell receptor associated protein kinase 70kDa
• Database Link:
  NP_001070
  Entrez Gene 22637 MouseEntrez Gene 301348 RatEntrez Gene 7535 Human
  UniProt ID P43403
• Synonyms: SRK; STCD; STD; TZK; ZAP-70
• Note: Zap-70 (Phospho-Tyr319) antibody detects endogenous levels of Zap-70 only when phosphorylated at tyrosine 319. This antibody may cross-react with Syk when phosphorylated at equivalent sites.

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Natural killer cell mediated cytotoxicity, Primary immunodeficiency, T cell receptor signaling pathway