AIRE Rabbit Polyclonal Antibody

CAT#: TA313461

Rabbit polyclonal AIRE (Ser156) antibody(Phospho-specific)

Product Images

Western blot analysis of extracts from HeLa cells, treated with Hu (2nM, 24hours), using AIRE (Phospho-Ser156) antibody.The lane on the right is treated with the synthesized peptide.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~1:3000, ELISA: 1:1000
• Reactivities: Human
• Modifications: Phospho-specific
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human AIRE around the phosphorylation site of serine 156 (P-G-SP-Q-L).
• Formulation: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: autoimmune regulator
• Database Link:
  NP_000374
  Entrez Gene 326 Human
  UniProt ID O43918
• Synonyms: AIRE1; APECED; APS1; APSI; PGA1
• Note: AIRE (Phospho-Ser156) antibody detects endogenous levels of AIRE only when phosphorylated at serine 156.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Primary immunodeficiency, Ubiquitin mediated proteolysis